| MLS 2020 | ||||
| 1ª Semana | ||||
| 29-feb-2020 | Washington | DC United | 1 | Canouse |
| Rapids | 2 | Kamara, Lewis | ||
| 29-feb-2020 | Montreal | Impact | 2 | Quioto, Urruti |
| Revolution | 1 | Bunbury | ||
| 29-sep-2020 | Houston | Dynamo | 1 | Manotas |
| Galaxy | 1 | Pavon | ||
| 29-feb-2020 | San Jose | Earthquakes | 2 | Rios, Alanis |
| Toronto | 2 | Pozuelo (P), Laryea | ||
| 29-feb-2020 | Frisco | Dallas | 2 | Ondrasek, Pomykal |
| Union | 0 | |||
| 29-feb-2020 | Orlando | Orlando City | 0 | |
| Real Salt Lake | 0 | |||
| 29-feb-2020 | Nashville | Nashville | 1 | Zimmerman |
| Atlanta United | 2 | Barco, Hyndman | ||
| 1-mar-2020 | Vancouver | Whitecaps | 1 | Nerwinski |
| Sporting | 3 | Pulido, Kinda, Hurtado | ||
| 1-mar-2020 | Columbus | Crew | 1 | Zelarayan |
| New York City | 0 | |||
| 1-mar-2020 | Harrison | Red Bulls | 3 | Duncan, Romero, Royer |
| Cincinnati | 2 | Cruz, Locadia | ||
| 1-mar-2020 | Seattle | Sounders | 2 | Morris (2) |
| Fire | 1 | Beric | ||
| 1-mar-2020 | Los Angeles | Los Angeles FC | 1 | Vela |
| Inter | 0 | |||
| 1-mar-2020 | Portland | Timbers | 1 | Valeri (P) |
| Minnesota United | 3 | Molino (2), Amarilla | ||
| 2ª Semana | ||||
| 7-mar-2020 | Foxborough | Revolution | 1 | Buksa |
| Fire | 1 | Bornstein | ||
| 7-mar-2020 | Sandy | Real Salt Lake | 1 | Kreilach |
| Red Bulls | 1 | Casseres | ||
| 7-mar-2020 | Frisco | Dallas | 2 | Ondrasek, Pepi |
| Impact | 2 | Urruti (2) | ||
| 7-mar-2020 | Washington | DC United | 2 | Asad (P), Brillant |
| Inter | 1 | Pizarro | ||
| 7-mar-2020 | Toronto | Toronto | 1 | Achara |
| New York City | 0 | |||
| 7-mar-2020 | Atlanta | Atlanta United | 2 | Barco, Hyndman |
| Cincinnati | 1 | Kubo | ||
| 7-mar-2020 | San Jose | Earthquakes | 2 | Eriksson (P), Qazaishvili |
| Minnesota United | 5 | Opara (2), Gregus, Amarilla, Lod | ||
| 7-mar-2020 | Kansas City | Sporting | 4 | Pulido, Espinoza, Kinda, Shelton |
| Dynamo | 0 | |||
| 7-mar-2020 | Commerce City | Rapids | 2 | Namli, Moor |
| Orlando City | 1 | Mueller | ||
| 8-mar-2020 | Carson | Galaxy | 0 | |
| Whitecaps | 1 | Ricketts | ||
| 8-mar-2020 | Seattle | Sounders | 1 | Ruidiaz (P) |
| Crew | 1 | Zardes | ||
| 8-mar-2020 | Portland | Timbers | 1 | Valeri |
| Nashville | 0 | |||
| 8-mar-2020 | Los Angeles | Los Angeles FC | 3 | Vela, Rossi, Segura |
| Union | 3 | Santos, Glesnes, Aaronson | ||
| 3ª Semana | ||||
| 13-ago-2020 | Frisco | Dallas | 0 | |
| Nashville | 1 | Accam | ||
| 17-ago-2020 | Frisco | Dallas | 0 | |
| Nashville | 0 | |||
| 19-ago-2020 | Toronto | Toronto | 3 | Piatti (2), DeLeon |
| Whitecaps | 0 | |||
| 20-ago-2020 | Harrison | Red Bulls | 1 | Duncan |
| New York City | 0 | |||
| 20-ago-2020 | Columbus | Crew | 3 | Etienne, Nagbe, Zardes |
| Fire | 0 | |||
| 20-ago-2020 | Foxborough | Revolution | 0 | |
| Union | 0 | |||
| 21-ago-2020 | Cincinnati | Cincinnati | 0 | |
| DC United | 0 | |||
| 21-ago-2020 | Saint Paul | Minnesota United | 1 | Lindsey (A) |
| Sporting | 2 | Kinda, Boxall (A) | ||
| 21-ago-2020 | Houston | Dynamo | 0 | |
| Dallas | 0 | |||
| 21-ago-2020 | Toronto | Toronto | 1 | Laryea |
| Whitecaps | 0 | |||
| 22-ago-2020 | Los Angeles | Los Angeles FC | 0 | |
| Galaxy | 2 | Zubak, Lletget | ||
| 22-ago-2020 | Atlanta | Atlanta United | 2 | Martinez (2) |
| Nashville | 0 | |||
| 22-ago-2020 | Fort Lauderdale | Inter | 3 | Carranza (2), Pizarro |
| Orlando City | 2 | Dike, Nani | ||
| 22-ago-2020 | Commerce City | Rapids | 1 | Herrera (A) |
| Real Salt Lake | 4 | Kreilach, Chang, Baird, Meram | ||
| 23-ago-2020 | Portland | Timbers | 0 | |
| Sounders | 3 | Ruidiaz (2), Ledezma | ||
| 4ª Semana | ||||
| 24-ago-2020 | Harrison | New York City | 1 | Ring |
| Crew | 0 | |||
| 25-ago-2020 | Washington | DC United | 1 | Kamara (P) |
| Revolution | 2 | Bou, Bunbury | ||
| 25-ago-2020 | Bridgeview | Fire | 3 | Herbers, Medran, Aliseda |
| Cincinnati | 0 | |||
| 25-ago-2020 | Chester | Union | 1 | Przybylko |
| Red Bulls | 0 | |||
| 25-ago-2020 | Montreal | Impact | 2 | Quioto, Lappalainen |
| Whitecaps | 0 | |||
| 25-ago-2020 | Kansas City | Sporting | 2 | Russell, Kinda |
| Dynamo | 5 | Elis, Ramirez, Hansen, Quintero (2) | ||
| 26-ago-2020 | Orlando | Orlando City | 3 | Mueller, Dike (2) |
| Nashville | 1 | Romney | ||
| 28-ago-2020 | Montreal | Impact | 0 | |
| Toronto | 1 | Pozuelo (P) | ||
| 29-ago-2020 | Atlanta | Atlanta United | 1 | Lennon |
| Orlando City | 3 | Junior Urso, Mueller, Nani | ||
| 29-ago-2020 | Cincinnati | Cincinnati | 0 | |
| Crew | 0 | |||
| 29-ago-2020 | Chester | Union | 4 | Przybylko (2), Sergio Santos, Aaronson |
| DC United | 1 | Gressel | ||
| 29-ago-2020 | Harrison | New York City | 3 | Parks, Tinnerholm, Ring |
| Fire | 1 | Pineda | ||
| 29-ago-2020 | Foxborough | Revolution | 1 | Bou |
| Red Bulls | 1 | Fernandez | ||
| 29-ago-2020 | Frisco | Dallas | 3 | Picault, Ferreira, Ziegler (P) |
| Minnesota United | 1 | Dotson | ||
| 29-ago-2020 | Commerce City | Rapids | 1 | Bassett |
| Sporting | 1 | Busio | ||
| 29-ago-2020 | Carson | Galaxy | 3 | Steres, Pavon (P), Lletget |
| Earthquakes | 2 | Qazaishvili, Cowell | ||
| 29-ago-2020 | Portland | Timbers | 4 | Chara, Niezgoda, Blanco, Mora |
| Real Salt Lake | 4 | Baird, Kreilach, Rossi, Johnson | ||
| 30-ago-2020 | Nashville | Nashville | 1 | Godoy |
| Inter | 0 | |||
| 30-ago-2020 | Seattle | Sounders | 3 | Ruidiaz, Morris (2) |
| Los Angeles FC | 1 | Rossi | ||
| 5ª Semana | ||||
| 1-sep-2020 | Toronto | Toronto | 0 | |
| Impact | 1 | Camacho | ||
| 2-sep-2020 | Atlanta | Atlanta United | 0 | |
| Inter | 0 | |||
| 2-sep-2020 | Cincinnati | Cincinnati | 0 | |
| Fire | 0 | |||
| 2-sep-2020 | Columbus | Crew | 1 | Zelarayan |
| Union | 0 | |||
| 2-sep-2020 | Harrison | Red Bulls | 0 | |
| DC UNited | 1 | Sorga | ||
| 2-sep-2020 | Houston | Dynamo | 3 | Quintero, Lassiter (2) |
| Minnesota United | 0 | |||
| 2-sep-2020 | Foxborough | Revolution | 0 | |
| New York City | 2 | Mancienne (A), Heber | ||
| 2-sep-2020 | Kansas City | Sporting | 1 | Shelton |
| Dallas | 1 | Jara | ||
| 2-sep-2020 | Nashville | Nashville | 1 | Leal |
| Orlando City | 1 | Michel | ||
| 2-sep-2020 | Sandy | Real Salt Lake | 2 | Glad, Ruiz |
| Sounders | 2 | Lodeiro (P), Gomez | ||
| 2-sep-2020 | Portland | Timbers | 2 | Mora, Valeri |
| Galaxy | 3 | Alvarez, Pavon, Corona | ||
| 2-sep-2020 | Los Angeles | Los Angeles FC | 5 | Rossi (2), Wright-Phillips, Cifuentes, Musovski |
| Earthquakes | 1 | Hoesen | ||
| 5-sep-2020 | Houston | Dynamo | 2 | Elis, Manotas |
| Sporting | 1 | Hurtado | ||
| 5-sep-2020 | Orlando | Orlando City | 1 | Michel |
| Atlanta United | 1 | Jahn | ||
| 5-sep-2020 | Vancouver | Whitecaps | 3 | Cavallini, Baldisimo, Nerwinski |
| Toronto | 2 | Osorio, Pozuelo | ||
| 5-sep-2020 | San Jose | Earthquakes | 1 | Wondolowski (P) |
| Rapids | 1 | Kamara | ||
| 6-sep-2020 | Washington | DC UNited | 0 | |
| New York City | 0 | |||
| 6-sep-2020 | Harrison | Red Bulls | 0 | |
| Union | 3 | Aaronson, Przybylko, Real | ||
| 6-sep-2020 | Bridgeview | Fire | 1 | Herbers |
| Revolution | 2 | Bunbury (2) | ||
| 6-sep-2020 | Columbus | Crew | 3 | Pedro Santos, Zardes (2) |
| Cincinnati | 0 | |||
| 6-sep-2020 | Saint Paul | Minnesota United | 4 | Gasper, Lod (2), Hayes |
| Real Salt Lake | 0 | |||
| 6-sep-2020 | Fort Lauderdale | Inter | 0 | |
| Nashville | 0 | |||
| 6-sep-2020 | Seattle | Sounders | 1 | Leerdam |
| Timbers | 2 | Williamson, Mora | ||
| 6-sep-2020 | Carson | Galaxy | 3 | Pavon, Lletget (2) |
| Los Angeles FC | 0 | |||
| 6ª Semana | ||||
| 9-sep-2020 | Fort Lauderdale | Inter | 2 | Morgan (2) |
| Atlanta United | 1 | Remedi | ||
| 9-sep-2020 | Saint Paul | Minnesota United | 3 | Toye, Molino (2, 1P) |
| Dallas | 2 | Pepi, Mosquera | ||
| 9-sep-2020 | Montreal | Impact | 1 | Wanyama |
| Toronto | 2 | Piatti, Altidore | ||
| 9-sep-2020 | Commerce City | Rapids | 1 | Abubakar |
| Dynamo | 1 | Ramirez | ||
| 9-sep-2020 | Sandy | Real Salt Lake | 3 | Kreilach, Meram, Rusnak (P) |
| Los Angeles FC | 0 | |||
| 9-sep-2020 | Seattle | Sounders | 7 | Morris, Ruidiaz (2), Leerdam, Jones (2), Joao Paulo |
| Earthquakes | 1 | Wondolowski (P) | ||
| 12-sep-2020 | Bridgeview | Fire | 2 | Mihailovic, Beric |
| Crew | 2 | Alashe, Zardes | ||
| 12-sep-2020 | Washington | DC United | 0 | |
| Red Bulls | 2 | Long, Royer | ||
| 12-sep-2020 | Harrison | New York City | 2 | Ring, Tinnerholm |
| Cincinnati | 1 | Vazquez | ||
| 12-sep-2020 | Orlando | Orlando City | 2 | Reyes (A), Pereyra |
| Inter | 1 | Shea | ||
| 12-sep-2020 | Chester | Union | 2 | Fontana (2) |
| Revolution | 1 | Buchanan | ||
| 12-sep-2020 | Nashville | Nashville | 4 | Badji, Mukhtar, McCarthy, Danladi |
| Atlanta United | 2 | Larentowicz, Bello | ||
| 12-sep-2020 | Frisco | Dallas | 2 | Ricaurte, Jara |
| Dynamo | 1 | Rodriguez | ||
| 12-sep-2020 | Sandy | Real Salt Lake | 0 | |
| Rapids | 5 | Rubio (2), Vines, Galvan, Bassett | ||
| 13-sep-2020 | Kansas City | Sporting | 1 | Russell |
| Minnesota United | 0 | |||
| 13-sep-2020 | Vancouver | Whitecaps | 2 | Bair, Camacho (A) |
| Impact | 4 | Okwonkwo, Taider (P), Piette, Quioto | ||
| 13-sep-2020 | Los Angeles | Los Angeles FC | 4 | Kaye, Rossi, Wright-Phillips, Musovski |
| Timbers | 2 | Williamson, Ebobisse | ||
| 13-sep-2020 | San Jose | Earthquakes | 0 | |
| Galaxy | 0 | |||
| 7ª Semana | ||||
| 16-sep-2020 | Frisco | Dallas | 4 | Mosquera (3), Jara |
| Rapids | 1 | Shinyashiki | ||
| 16-sep-2020 | San Jose | Earthquakes | 1 | Qazaishvili |
| Timbers | 1 | Chara | ||
| 16-sep-2020 | Vancouver | Whitecaps | 3 | Montero (2, 1P), Dajome |
| Impact | 1 | Quioto | ||
| 18-sep-2020 | Seattle | Sounders | 3 | Lodeiro (2P), Ruidiaz |
| Los Angeles FC | 0 | |||
| 19-sep-2020 | Kansas City | Sporting | 2 | Russell (2) |
| Dallas | 3 | Jara (2), Hollingshead | ||
| 19-sep-2020 | Foxborough | Revolution | 0 | |
| New York City | 0 | |||
| 19-sep-2020 | Atlanta | Atlanta United | 1 | Gallagher |
| Inter | 2 | Agudelo, Shea | ||
| 19-sep-2020 | Harrison | Red Bulls | 0 | |
| Cincinnati | 1 | Medunjanin | ||
| 19-sep-2020 | Washington | DC United | 2 | Kamara, Yow |
| Toronto | 2 | Pozuelo, Akinola | ||
| 19-sep-2020 | Columbus | Crew | 2 | Pedro Santos, Zardes |
| Nashville | 0 | |||
| 19-sep-2020 | Orlando | Orlando City | 4 | Mueller, Nani, Junior Urso, Michel |
| Fire | 1 | Beric (P) | ||
| 19-sep-2020 | Houston | Dynamo | 2 | Quintero, Figueroa |
| Minnesota United | 2 | Molino, Lod | ||
| 19-sep-2020 | Sandy | Real Salt Lake | 1 | Meram |
| Whitecaps | 2 | Milinkovic, Cavallini | ||
| 19-sep-2020 | San Jose | Earthquakes | 1 | Fierro |
| Timbers | 6 | Valeri (2, 1P), Ebobisse, Chara, Cascante, Niezgoda | ||
| 19-sep-2020 | Carson | Galaxy | 0 | |
| Rapids | 2 | Bassett, Lewis | ||
| 20-sep-2020 | Montreal | Impact | 1 | Quioto |
| Union | 4 | Bedoya, Przybylko (2), Fontana | ||
| 8ª Semana | ||||
| 23-sep-2020 | Foxborough | Revolution | 3 | Kessler, Bou, Fagundez |
| Impact | 1 | Lappalainen | ||
| 23-sep-2020 | Harrison | New York City | 0 | |
| Toronto | 1 | Pozuelo (P) | ||
| 23-sep-2020 | Atlanta | Atlanta United | 1 | Larentowicz (P) |
| Dallas | 0 | |||
| 23-sep-2020 | Kansas City | Sporting | 1 | Russell |
| Orlando City | 2 | Akindele, Michel | ||
| 23-sep-2020 | Columbus | Crew | 2 | Zelarayan, Pedro Santos |
| Minnesota United | 1 | Lod | ||
| 23-sep-2020 | Cincinnati | Cincinnati | 0 | |
| Union | 0 | |||
| 23-sep-2020 | Bridgeview | Fire | 4 | Beric, Herbers, Medran, Sapong (P) |
| Dynamo | 0 | |||
| 23-sep-2020 | Fort Lauderdale | Inter | 1 | Agudelo |
| Red Bulls | 4 | Egbo (P), White, Mines, Royer | ||
| 23-sep-2020 | Nashville | Nashville | 1 | Rios |
| DC United | 0 | |||
| 23-sep-2020 | Commerce City | Rapids | 5 | Bassett, Lewis, Thompson (A), Mezquida, Shinyashiki |
| Earthquakes | 0 | |||
| 23-sep-2020 | Sandy | Real Salt Lake | 2 | Rusnak (P), Kreilach |
| Galaxy | 0 | |||
| 23-sep-2020 | Portland | Timbers | 1 | Chara |
| Sounders | 0 | |||
| 23-sep-2020 | Los Angeles | Los Angeles FC | 6 | Jakovic, Wright-Phillips (2), Veselinovic (A), Rossi, Rose (A) |
| Whitecaps | 0 | |||
| 26-sep-2020 | Nashville | Nashville | 1 | Rios |
| Dynamo | 1 | Figueroa | ||
| 26-sep-2020 | Harrison | New York City | 4 | Mitrita (2), Tinnerholm, Medina |
| Cincinnati | 0 | |||
| 27-sep-2020 | Harrison | Red Bulls | 4 | Barlow (2), Royer, Romero |
| Impact | 1 | Bojan Krkic | ||
| 27-sep-2020 | Washington | DC United | 0 | |
| Revolution | 2 | Bou, Buksa | ||
| 27-sep-2020 | Bridgeview | Fire | 2 | Herbers, Beric |
| Atlanta United | 0 | |||
| 27-sep-2020 | Toronto | Toronto | 3 | Altidore, Pozuelo, Laryea |
| Crew | 1 | Mavinga (A) | ||
| 27-sep-2020 | Chester | Union | 3 | Fontana, Ilsinho, Aaronson |
| Inter | 0 | |||
| 27-sep-2020 | Saint Paul | Minnesota United | 0 | |
| Real Salt Lake | 0 | |||
| 27-sep-2020 | Frisco | Dallas | 0 | |
| Orlando City | 0 | |||
| 27-sep-2020 | Vancouver | Whitecaps | 0 | |
| Timbers | 1 | Mora | ||
| 27-sep-2020 | Los Angeles | Los Angeles FC | 1 | Kaye |
| Earthquakes | 2 | Salinas, Yueill | ||
| 27-sep-2020 | Carson | Galaxy | 1 | Lletget |
| Sounders | 3 | Roldan (2), Morris | ||
| 9ª Semana | ||||
| 3-oct-2020 | Orlando | Orlando City | 3 | Dike, Urso, Antonio Carlos |
| Red Bulls | 1 | Valot | ||
| 3-oct-2020 | Washington | DC United | 0 | |
| Atlanta United | 4 | Gallagher (2), Lennon, Jahn | ||
| 3-oct-2020 | Montreal | Impact | 2 | Lappalainen, Urruti |
| Fire | 2 | Beric, Calvo | ||
| 3-oct-2020 | Foxborough | Revolution | 0 | |
| Nashville | 0 | |||
| 3-oct-2020 | Toronto | Toronto | 2 | Akinola, Pozuelo |
| Union | 1 | Sergio Santos | ||
| 3-oct-2020 | Houston | Dynamo | 1 | Junqua |
| Sporting | 2 | Pulido (2) | ||
| 3-oct-2020 | Fort Lauderdale | Inter | 2 | Morgan (2) |
| New York City | 3 | Mitrita (2), Tinnerholm | ||
| 3-oct-2020 | Saint Paul | Minnesota United | 2 | Kamara (P), Molino |
| Cincinnati | 0 | |||
| 3-oct-2020 | Frisco | Dallas | 2 | Barrios, Ziegler (P) |
| Crew | 2 | Mokhtar, Pedro Santos | ||
| 3-oct-2020 | Seattle | Sounders | 3 | Joao Paulo, Godoy (A), Ruidiaz |
| Whitecaps | 1 | Montero (P) | ||
| 3-oct-2020 | San Jose | Earthquakes | 2 | Lopez, Rios (P) |
| Galaxy | 1 | Lletget | ||
| 4-oct-2020 | Sandy | Real Salt Lake | 1 | Atuesta (A) |
| Los Angeles FC | 3 | Wrght-Phillips, Rossi, Rodriguez | ||
| 10ª Semana | ||||
| 6-oct-2020 | Nashville | Nashville | 0 | |
| Minnesota United | 0 | |||
| 7-oct-2020 | Atlanta | Atlanta United | 0 | |
| Orlando City | 0 | |||
| 7-oct-2020 | Harrison | Red Bulls | 1 | Fernandez |
| Inter | 2 | Pellegrini, Higuain | ||
| 7-oct-2020 | Foxborough | Revolution | 0 | |
| Toronto | 1 | Akinola | ||
| 7-oct-2020 | Chester | Union | 3 | Ilsinho, Bedoya, Elliot |
| Cincinnati | 0 | |||
| 7-oct-2020 | Columbus | Crew | 1 | Zardes |
| Impact | 2 | Lappalainen, Krkic (P) | ||
| 7-oct-2020 | Houston | Dynamo | 2 | Quintero, Ceren (P) |
| Dallas | 0 | |||
| 7-oct-2020 | Bronx | New York City | 4 | Castellanos (P), Tajouri (2, 1P), Parks |
| DC United | 1 | Kamara (P) | ||
| 7-oct-2020 | Kansas City | Sporting | 1 | Reid |
| Fire | 0 | |||
| 7-oct-2020 | Seattle | Sounders | 2 | Morris, Gomez |
| Real Salt Lake | 1 | Tolo (A) | ||
| 7-oct-2020 | Carson | Galaxy | 3 | Araujo, Zubak, Pavon |
| Timbers | 6 | Mora (2), Ebobisse (2), Valeri, Mabiala | ||
| 7-oct-2020 | San Jose | Earthquakes | 3 | Espinoza, Rios, Marie |
| Whitecaps | 0 | |||
| 10-oct-2020 | Fort Lauderdale | Inter | 1 | Morgan (P) |
| Dynamo | 0 | |||
| 10-oct-2020 | Atlanta | Atlanta United | 0 | |
| Red Bulls | 1 | Clark | ||
| 10-oct-2020 | Vancouver | Whitecaps | 2 | Martinez (A), Cavallini |
| Real Salt Lake | 1 | Kreilach | ||
| 11-oct-2020 | Bronx | New York City | 1 | Callens |
| Revolution | 2 | Bunbury, Nguyen (P) | ||
| 11-oct-2020 | Los Angeles | Los Angeles FC | 3 | Musovski (2), Ginella |
| Sounders | 1 | Lodeiro | ||
| 11-oct-2020 | Bridgeview | Fire | 2 | Sapong, Sekulic |
| DC United | 1 | Bornstein (A) | ||
| 11-oct-2020 | Cincinnati | Cincinnati | 0 | |
| Toronto | 1 | Mullins | ||
| 11-oct-2020 | Chester | Union | 2 | Jamiro, Sergio Santos |
| Impact | 1 | Sejdic | ||
| 11-oct-2020 | Kansas City | Sporting | 2 | Fernandes, Hurtado |
| Nashville | 1 | Zimmerman | ||
| 11-oct-2020 | Portland | Timbers | 3 | Niezgoda (2), Mora |
| Earthquakes | 0 | |||
| 11ª Semana | ||||
| 14-oct-2020 | Montreal | Impact | 2 | Sejdic, Tabla |
| Revolution | 3 | Manneh, Bunbury, Buksa | ||
| 14-oct-2020 | Cincinnati | Cincinnati | 2 | Kubo (P), Hagglund |
| Crew | 1 | Pedro Santos (P) | ||
| 14-oct-2020 | Orlando | Orlando City | 1 | Mueller |
| New York City | 1 | Parks | ||
| 14-oct-2020 | Toronto | Toronto | 1 | Pozuelo (P) |
| Red Bulls | 1 | Clark | ||
| 14-oct-2020 | Washington | DC United | 2 | Pines, Asad (P) |
| Union | 2 | Fontana, McKenzie | ||
| 14-oct-2020 | Houston | Dynamo | 1 | Quintero |
| Nashville | 3 | Mukhtar (2), Danladi | ||
| 14-oct-2020 | Fort Lauderdale | Miami | 1 | Shea |
| Atlanta United | 1 | Mulraney | ||
| 14-oct-2020 | Frisco | Dallas | 1 | Hollingshead |
| Sporting | 0 | |||
| 14-oct-2020 | Sandy | Real Salt Lake | 2 | Martinez, Kreilach |
| Timbers | 1 | Tuiloma | ||
| 14-oct-2020 | Vancouver | Whitecaps | 2 | Cavallini (2) |
| Los Angeles FC | 1 | Atuesta (P) | ||
| 14-oct-2020 | Carson | Galaxy | 0 | |
| Earthquakes | 4 | Lima (2), Rios, Thompson | ||
| 17-oct-2020 | Bridgeview | Fire | 2 | Beric, Mihailovic |
| Sporting | 2 | Hurtado, Kinda | ||
| 17-oct-2020 | Montreal | Impact | 2 | Bojan, Urruti |
| Inter | 1 | Shea | ||
| 18-oct-2020 | Columbus | Crew | 3 | Artur, Pedro Santos, Zardes |
| New York City | 1 | Castellanos | ||
| 18-oct-2020 | Harrison | Red Bulls | 1 | White |
| Orlando City | 1 | Nani (P) | ||
| 18-oct-2020 | Cincinnati | Cincinnati | 1 | Vazquez |
| DC United | 2 | Pines, Odoi-Atsem | ||
| 18-oct-2020 | Toronto | Toronto | 1 | Piatti |
| Atlanta United | 0 | |||
| 18-oct-2020 | Saint Paul | Minnesota | 2 | Finlay (2) |
| Dynamo | 2 | Rodriguez, Hansen | ||
| 18-oct-2020 | Portland | Timbers | 1 | Ebobisse |
| Los Angeles FC | 1 | Torres | ||
| 18-oct-2020 | Carson | Galaxy | 1 | Koreniuk |
| Whitecaps | 0 | |||
| 18-oct-2020 | San Jose | Earthquakes | 0 | |
| Sounders | 0 | |||
| 19-oct-2020 | Foxborough | Revolution | 1 | Buchanan |
| Union | 2 | Farrell (A), Fontana | ||
| 12ª Semana | ||||
| 20-oct-2020 | Nashville | Nashville | 3 | Leal, Cadiz, Rios |
| Dallas | 0 | |||
| 22-oct-2020 | Seattle | Sounders | 1 | Bruin |
| Timbers | 1 | Flores | ||
| 23-oct-2020 | Nashville | Nashville | 1 | Zimmerman |
| Revolution | 1 | Buksa | ||
| 24-oct-2020 | Fort Lauderdale | Inter | 2 | Jansson (A), Gonzalez Pirez |
| Orlando City | 1 | Dike | ||
| 24-oct-2020 | Atlanta | Atlanta United | 1 | Gallagher |
| DC United | 2 | Canouse, Rivas | ||
| 24-oct-2020 | Bronx | New York City | 3 | Medina, Moralez, Rocha |
| Montreal | 1 | Quioto | ||
| 24-oct-2020 | Bridgeview | Fire | 2 | Beric, Frankowski |
| Red Bulls | 2 | Duncan, White | ||
| 24-oct-2020 | Cincinnati | Cincinnati | 0 | |
| Minnesota | 1 | Schoenfeld | ||
| 24-oct-2020 | Chester | Union | 5 | Sergio Santos (3), McKenzie, Jamiro |
| Toronto | 0 | |||
| 24-oct-2020 | Houston | Dynamo | 1 | Rodriguez |
| Crew | 1 | Cabrera (A) | ||
| 24-oct-2020 | Kansas City | Sporting | 4 | Pulido, Fontas, Kinda, Fernandes |
| Rapids | 0 | |||
| 24-oct-2020 | Sandy | Real Salt Lake | 0 | |
| Dallas | 0 | |||
| 24-oct-2020 | Vancouver | Whitecaps | 2 | Adnan, Ricketts |
| Earthquakes | 1 | Fierro | ||
| 25-oct-2020 | Los Angeles | Los Angeles FC | 2 | Musovski, Vela |
| Galaxy | 0 | |||
| 13ª Semana | ||||
| 27-oct-2020 | Montreal | Impact | 0 | |
| Nashville | 1 | Leal | ||
| 27-oct-2020 | Vancouver | Whitecaps | 0 | |
| Sounders | 2 | Ruidiaz, Lodeiro | ||
| 28-oct-2020 | Harrison | Red Bulls | 1 | Long |
| Revolution | 0 | |||
| 28-oct-2020 | Cincinnati | Cincinnati | 0 | |
| Sporting | 1 | Espinoza | ||
| 28-oct-2020 | Orlando | Orlando City | 4 | Dike, Mueller, Akindele, Barrozo |
| Atlanta United | 1 | Torres | ||
| 28-oct-2020 | Chester | Union | 2 | Przybylko (P), Burke |
| Fire | 1 | Beric | ||
| 28-oct-2020 | Toronto | Toronto | 0 | |
| New York City | 1 | Medina | ||
| 28-oct-2020 | Saint Paul | Minnesota | 2 | Lod, Abubakar (A) |
| Rapids | 1 | Shinyashiki | ||
| 28-oct-2020 | Washington | DC United | 1 | Gressel |
| Crew | 0 | |||
| 28-oct-2020 | Frisco | Dallas | 2 | Jara (P), Hollingshead |
| Inter | 1 | Pizarro | ||
| 28-oct-2020 | Portland | Timbers | 5 | Niezgoda (2), Valeri (P), Williamson, Polo |
| Galaxy | 2 | Pavon (2) | ||
| 28-oct-2020 | Los Angeles | Los Angeles FC | 2 | Rossi, Segura |
| Dynamo | 1 | Lassiter | ||
| 28-oct-2020 | San Jose | Earthquakes | 2 | Wondolowski (2) |
| Real Salt Lake | 0 | |||
| 31-oct-2020 | Frisco | Dallas | 3 | Jara, Picault (2) |
| Dynamo | 0 | |||
| 31-oct-2020 | Nashville | Nashville | 1 | Rios |
| Fire | 1 | Sekulic | ||
| 1-nov-2020 | Columbus | Crew | 2 | Artur, Nemeth |
| Union | 1 | Jamiro (P) | ||
| 1-nov-2020 | Atlanta | Atlanta United | 2 | Jahn, Moreno (P) |
| Cincinnati | 0 | |||
| 1-nov-2020 | Bronx | New York City | 5 | Castellanos (3, 1P), Mackay-Steven, Ring |
| Red Bulls | 2 | White, Casseres | ||
| 1-nov-2020 | Montreal | Impact | 0 | |
| Orlando City | 1 | Dike | ||
| 1-nov-2020 | Foxborough | Revolution | 4 | Buksa, Canouse (A), Bunbury (2) |
| DC United | 3 | Asad, Yow, Rivas | ||
| 1-nov-2020 | Toronto | Toronto | 2 | Akinola, Pozuelo (P) |
| Inter | 1 | Matuidi | ||
| 1-nov-2020 | Commerce City | Rapids | 3 | Shinyashiki, Rosenberry, Bassett |
| Sounders | 1 | Morris | ||
| 2-nov-2020 | Portland | Timbers | 1 | Chara |
| Whitecaps | 0 | |||
| 2-nov-2020 | Carson | Galaxy | 2 | Gonzalez, Pavon |
| Real Salt Lake | 1 | Martinez | ||
| 14ª Semana | ||||
| 4-nov-2020 | Orlando | Orlando City | 2 | Mueller, Michel |
| Crew | 1 | Afful | ||
| 4-nov-2020 | Saint Paul | Minnesota United | 2 | Aja, Lodi |
| Fire | 2 | Beric, Pineda | ||
| 4-nov-2020 | Nashville | Nashville | 0 | |
| Dallas | 1 | Hollingshead | ||
| 5-nov-2020 | Portland | Timbers | 0 | |
| Rapids | 1 | Acosta | ||
| 5-nov-2020 | San Jose | Earthquakes | 3 | Atuesta (A), Wondolowski, Espinoza |
| Los Angeles FC | 2 | Blessing, Rossi | ||
| 5-nov-2020 | Carson | Galaxy | 1 | Hernandez |
| Sounders | 1 | Ruidiaz | ||
| 8-nov-2020 | Bridgeview | Fire | 3 | Beric, Frankowski (2) |
| New York City | 4 | Callens, Mackay-Steven, Medina, Castellanos | ||
| 8-nov-2020 | Columbus | Crew | 2 | Zelarayan, Zardes |
| Atlanta United | 1 | Moreno (P) | ||
| 8-nov-2020 | Washington | DC United | 2 | Pines, Kamara |
| Impact | 3 | Krkic, Wanyama, Quioto | ||
| 8-nov-2020 | Fort Lauderdale | Inter | 2 | Ambrose, Gonzalez |
| Cincinnati | 1 | Gyau | ||
| 8-nov-2020 | Harrison | Red Bulls | 2 | Barlow, White |
| Toronto | 1 | Endoh | ||
| 8-nov-2020 | Orlando | Orlando City | 2 | Dike, Nani |
| Nashville | 3 | Lovitz, Mukhtar, Cadiz | ||
| 8-nov-2020 | Chester | Union | 2 | Sergio Santos, Burke |
| Revolution | 0 | |||
| 8-nov-2020 | Houston | Dynamo | 1 | Manotas |
| Rapids | 2 | Namli, Rubio | ||
| 8-nov-2020 | Los Angeles | Los Angeles FC | 1 | Vela |
| Timbers | 1 | Villafaña | ||
| 8-nov-2020 | Saint Paul | Minnesota United | 3 | Molino (2), Reynoso |
| Dallas | 0 | |||
| 8-nov-2020 | Sandy | Real Salt Lake | 0 | |
| Sporting | 2 | Shelton, Hurtado | ||
| 8-nov-2020 | Seattle | Sounders | 4 | Lodeiro, Ruidiaz, Morris, Lopez (A) |
| Earthquakes | 1 | Lopez | ||
| 8-nov-2020 | Vancouver | Whitecaps | 3 | Cavallini, Montero (2) |
| Galaxy | 0 | |||
| Repechaje | ||||
| 20-nov-2020 | Foxborough | Revolution | 2 | Gil, Bou |
| Impact | 1 | Quioto | ||
| 20-nov-2020 | Nashville | Nashville | 3 | Lea, Mukhtar (P), McCarty |
| Inter | 0 | |||
| 4º Final Conferencia | ||||
| 21-nov-2020 | Orlando | Orlando | 1(6) | Nani (P) |
| New York City | 1(5) | Quioto | ||
| 21-nov-2020 | Columbus | Crew | 3 | Pedro Santos (P), Nagbe, Zardes |
| Red Bulls | 2 | Clark, White | ||
| 21-nov-2020 | Saint Paul | Minnesota United | 3 | Molina (2), Lod |
| Rapids | 0 | |||
| 22-nov-2020 | Kansas City | Sporting | 3(3) | Espinoza, Ilie, Busio |
| Earthquakes | 3(0) | Fierro, Salinas, Wondolowski | ||
| 23-nov-2020 | Portland | Timbers | 1(7) | Villafaña |
| Dallas | 1(8) | Pepi | ||
| 24-nov-2020 | Toronto | Toronto | 0 | |
| Nashville | 1 | Rios | ||
| 24-nov-2020 | Chester | Union | 0 | |
| Revolution | 2 | Buksa, Buchanan | ||
| 25-nov-2020 | Seattle | Sounders | 3 | Lodeiro, Ruidiaz, Morris |
| Los Angeles FC | 1 | Atuesta | ||
Semifinales
de Conferencia |
||||
| 29-nov-2020 | Orlando | Orlando | 1 | Junior Urso |
| Revolution | 3 | Gil (P), Bou (2) | ||
| 29-nov-2020 | Columbus | Crew | 2 | Pedro Santos, Zardes |
| Nashville | 0 | |||
| 1-dic-2020 | Seattle | Sounders | 1 | O'Neill |
| Dallas | 0 | |||
| 3-dic-2020 | Kansas City | Sporting | 0 | |
| Minnesota United | 3 | Molino (2), Dibassy | ||
Finales
de Conferencia |
||||
| 6-dic-2020 | Columbus | Crew | 1 | Artur |
| Revolution | 0 | |||
| 7-dic-2020 | Seattle | Sounders | 3 | Bruin, Ruidiaz, Svensson |
| Minnesota United | 2 | Reynoso, Dibassy | ||
| FINAL MLS | ||||
| 12-dic-2020 | Columbus | Crew | 3 | Zelarayan (2), Etienne |
| Sounders | 0 | |||